People born with any of these types of SCD inherit the “S” sickle cell gene and another abnormal gene like “D”, “E” or “O”. There are other rare kinds of SCD such as HbSD, HbSE and HbSO. : This is caused when a person inherits the S sickle cell gene from one of their parents, and from the other, gets a beta thalassemia gene.
: This is caused by inheritance of the genotype for sickle cell “S” from one parent and another abnormal gene called ‘‘C’’ from the other. This kind of SDC is usually called Sickle cell anemia and it occurs when an individual inherits a sickle cell gene (S) from each parent. The common types of sickle cell disease are:
Delayed growth caused by the inability of red blood cells to effectively transport nutrients and oxygen.Frequent infections in cases where the spleen becomes damaged, leaving the individual vulnerable to infections.Swollen limbs due to the obstruction of blood flow to the hands and feet.
Anemia: This is due to the premature death of red blood cells usually leading to a shortage in the amount of red blood cells in the blood. Sickle cell disease is characterized by symptoms like: As a result of this, oxygen is not transported to the tissues and this causes severe pain and in some cases damage to the oxygen deprived areas. This makes it difficult for the cells to move through blood vessels and they may clog up the vessels. Normal haemoglobin should be round and smooth but sickle cell disease makes it curved like a sickle and sticky. When a person is born with sickle cell disease, it means that the haemoglobin is sickle shaped. Having sickle cell disease means that the person inherits an abnormal haemoglobin gene from both birth parents. However, they can pass this gene onto their children. People who are born with a sickle cell trait do not usually experience any problems because the amount of sickle haemoglobin is not sufficient to cause sickle shaped cells. Having a sickle cell trait implies that a person inherits one copy of the genotype for sickle cell (S) from one of their parents and the normal gene A from the other parent. Haemoglobin functions as an oxygen transporter to all parts of the body. This protein is needed to produce the normal haemoglobin, which gives the genotype AA. When a child is born, they normally inherit two copies of the gene that produces a protein called beta-globin. This is why you and your partner should determine your biological compatibility before having a child to ensure you give that child the best chance at a healthy life. It is your responsibility as a parent to ensure to the best of your ability, that you have a healthy child. Deciding to have children biologically is a big deal. Healthy and active children can be a handful but not many parents will have it any other way.
0 kommentar(er)
